Engineering, applied biological sciences to "regenerate and durable small-diameter grafts as arterial catheters", by Morgan B. Elliott, Brian Ginn, Takuma Fukunishi, Djahida Bedja, Abhilash Suresh, Theresa Chen, Takahiro Inoue, Harry C Dietz, Lakshmi Santhanam, Hai-Quan Mao, Narutoshi Hibino and Sharon Gerecht, first published on June 10, 2019; 10.1073/pnas.1905966116 (Proc. Natl. Acad. Sci. USA 116, 12710–12719).

The author points out that the image shown in Figure 1D, ii is an unintentional repetition of a previously published image (1). The author provides a revised image that includes the correct image of ii in Figure 1D. The corrected figure and its legend are shown below. The authors confirmed that this change will not change the interpretation of the data or research conclusions. The online version has been corrected.

Preparation of hollow fibrin hydrogel microfibrous tube. The workflow starts with (A) fibrin hydrogel microfibers, and spins the fibrin hydrogel microfibers into thin sheets by grating the landing position of the biopolymer jet on the rotating collection solution. (B) The sheet is collected by placing a PTFE-coated mandrel on the resulting hydrogel sheet perpendicular or parallel to the fiber direction. (C) Then wrap the sheet (i), (ii) remove the PTFE-coated mandrel after dehydration, and (iii) produce a hollow fibrin tube with circumferential (left) or longitudinal (right) alignment. (D) Representative SEM micrographs of (i) circumferentially aligned hollow tubes and (ii) stretched and dried, longitudinally aligned fibrin fiber bundles. (iii) The orientation of the longitudinally aligned fibrin microfibers and (iv) the quantification of the orientation distribution of grafts dehydrated by graded ethanol and freeze-drying (Lyo) treatment, relative to the longitudinal graft axis (0°). (Scale bars: i, 200 µm; ii, 40 µm.) (E) (i and ii) Lyo-treated and (iii and iv) EtOH-treated longitudinally aligned hollow tubes are representative longitudinal and cross-sectional SEM micrographs. (Scale bar: 400 µm.) (F) Mechanical properties, including (i) modulus of elasticity, (ii) axial STF, (iii) axial UTS, (iv) toughness, and (v) dry fibrin tube The outer diameter Lyo and EtOH treatment (n = 3-5). *P <0.05; ****P <0.0001.

1. S. Zhang et al. Produce polymer hydrogel microfibers with internal arrangement through electrical and mechanical stretching. Biomaterials 35, 3243–3251 (2014).

Released under PNAS license.

Thank you for your interest in advertising on PNAS.

Note: We only ask you to provide your email address so that the people you recommend the page to know that you want them to see it, and that it is not spam. We do not capture any email addresses.

Feedback privacy/legal

Copyright © 2021 National Academy of Sciences. Online ISSN 1091-6490. PNAS is a partner of CHORUS, COPE, CrossRef, ORCID and Research4Life.